1. Overview of 2-Chlorobenzoic Acid
2-Chlorobenzoic Acid (CAS 118-91-2) is an ortho-substituted halogenated aromatic carboxylic acid, featuring high reactivity and regioselectivity for industrial directed organic synthesis.2-Chlorobenzoic acid is also known as ortho-chlorobenzoic acid, O-chlorobenzoic acid, and OCBA.
SNOWHITE CHEMICAL CO.,LTD supplies bulk industrial grade and high-purity pharmaceutical grade products, with mature ortho-position substitution synthesis technology and strict isomer control.
Our products are widely used in large-scale benzoylurea insecticide production, API synthesis, disperse dye manufacturing and specialty chemical processing worldwide.
1.1 Basic Chemical Information
Chemical Name: 2-Chlorobenzoic Acid (o-Chlorobenzoic Acid)
Molecular Formula: C7H5ClO2
Molecular Weight: 156.57g/mol
CAS No.: 118-91-2
HS Code: 29163900
1.2 Physicochemical Properties
Physical Form: White to off-white crystalline powder,
Melting Point: 138~143℃;
Boiling Point: 285℃;
Flash Point: 173℃
Density (25℃): 1.544 g/cm³;
Solubility: Slightly soluble in cold water;
Stability: Stable under dry & ambient conditions; avoid strong oxidizers and strong bases
1.3 Reaction Characteristics and Mechanism
The industrial application value of 2-Chlorobenzoic Acid comes from the synergistic effect of ortho-chloro substituent and carboxyl group:
- The carboxyl group undergoes esterification, amidation and salt formation stably, with high conversion efficiency for industrial synthesis
- The ortho-chlorine atom provides steric hindrance and electron-withdrawing effect, suppresses side reactions and improves reaction regioselectivity
- The structure ensures high biological activity of downstream agrochemicals and pharmaceuticals, suitable for large-scale industrial production
2. Agricultural Grade 2-Chlorobenzoic Acid
2.1 Product Overview
OCBA used for large-scale agrochemical, dye and fine chemical production, with cost advantages and stable batch consistency.
2.2 Typical Applications
Core intermediate for benzoylurea insecticides and acaricides; used for disperse dye synthesis to improve light/wash fastness, compatible with industrial production lines.
3. Pharmaceutical Grade 2-Chlorobenzoic Acid
3.1 Product Overview
Purity >99.0%, with strict control of isomers, heavy metals and organic impurities, compliant with pharmaceutical safety and quality requirements.2-Chlorobenzoic Acid for pharmaceutical use, complies with USP and BP.
3.2 Applications and Reaction Transformations
Used for API synthesis of NSAIDs, antipsychotics and antifungal drugs; ortho-chloro structure optimizes drug bioavailability and metabolic stability.
4. Synthesis Methods
Industrial production adopts two mature routes:
l Diazotization method: High selectivity, for pharmaceutical grade production
l Chlorination-hydrolysis method: Low cost, for large-scale industrial grade production
5. Quality
|
Analysis |
Units |
Standard |
|
APPEARANCE |
- |
WHITE POWDER |
|
WEIGHT LOSS |
% |
≤0.5% |
|
O- CHLOROBENZOIC ACID |
% |
≥99.0% |
|
BOILING POINT |
℃ |
285℃ |
|
MELTING POINT |
℃ |
139℃ |
|
Conclusion |
Qualified |
|
6. Packaging and Storage
6.1 Packaging
Standard: 25kg bags, customizable
6.2 Storage
Store in cool, dry, well-ventilated area below 30℃
Sealed to avoid moisture; keep away from oxidizers and strong bases
7. Supply and Technical Support
SNOWHITE CHEMICAL CO., LTD provides stable supply of industrial grade and pharmaceutical grade products, supported by full-process technical services covering production, application and logistics.
Our core competitive advantages:
ISO 9001 certified, with stable batch-to-batch quality
Mature ortho-substitution synthesis and strict isomer control technology
Stable large-scale production capacity with complete COA, SDS and TDS documents
Customized packaging and purity specifications for industrial and pharmaceutical applications
Contact Us
Contact SNOWHITE CHEMICAL CO.,LTD now to get COA, free samples and the latest quotation.
Email: shirley@snowhitechem.com
Phone: +86-25-56215758
WhatsApp：+86-13776524331
