1. Why 2-Chlorotoluene Matters in Real Manufacturing
2-Chlorotoluene (o-Chlorotoluene, CAS 95-49-8, formula C₇H₇Cl, molecular weight 126.58 g/mol) is typically purchased as a synthetic intermediate, not a finished product. In many routes, it’s chosen because the ortho-position chlorine can influence selectivity in downstream steps. For buyers, the real question is simple: will this lot run the same as your previous lot?
2. Practical Uses of 2-Chlorotoluene
If you’re searching “2-Chlorotoluene uses,” it usually refers to factory-side applications such as:
• Agrochemical intermediate: multi-step synthesis where controlled aromatic substitution is needed.
• Pharmaceutical intermediate (custom synthesis): a building block for routes sensitive to positional effects.
• Fine chemicals: dyes, specialty intermediates, and tailored synthesis using chlorinated aromatics.
Most supplier pages list industries; production teams care about repeatable yield and predictable work-up.
3. 2-Chlorotoluene vs 4-Chlorotoluene
2-Chlorotoluene (ortho-) brings more steric influence near reactive positions, which may affect selectivity in certain substitutions; 4-Chlorotoluene (para-) is more symmetric and often provides cleaner positional outcomes. If your downstream step is position-sensitive, choosing the wrong isomer can quietly create rework.
4. Key Properties
• Appearance: colorless to light yellow liquid
• Boiling point: ~158–160°C
• Density (20°C): ~1.07 g/cm³
• Flash point: ~47°C
• Solubility: practically insoluble in water; soluble in most common organic solvents
These ranges are widely used for procurement checks and process planning.
5. The 3 Things That Decide Yield
(1) Impurity profile (trace organics/isomer content): two “99%” products can behave differently in a real reaction.
(2) Moisture control: small water differences can affect catalysts, side reactions, and work-up efficiency.
(3) Batch-to-batch consistency: for manufacturing, consistency is a spec by itself.
6. Typical Industrial Specification
Common reference ranges for industrial supply:
• Assay (GC): ≥ 99.0%
• Moisture: ≤ 0.05%
• Acidity (as HCl): ≤ 0.01%
• Residue on evaporation: ≤ 0.02%
To improve reaction stability, request consistent impurity trends across lots, not only a single-lot “pass.”
7. Common Sourcing Mistakes
• Buying only on price and skipping a small trial lot
• Ignoring packaging choice (drums vs ISO tank affects handling and risk control)
• Not aligning COA items with the process pain points (e.g., moisture not tracked tightly)
FAQ
Q1: Is 2-Chlorotoluene the same as o-Chlorotoluene?
Yes. “2-Chlorotoluene” and “o-Chlorotoluene” refer to the same isomer (ortho-).
Q2: What should I check first when sourcing 2-Chlorotoluene in bulk?
Start with a recent COA and confirm the items that affect your process most—typically moisture, assay by GC, and whether the impurity trend is consistent across lots.
Q3: Why can two products with the same purity behave differently?
Because “purity” is one number. Trace isomers/organics and moisture differences can change selectivity, catalyst performance, or work-up efficiency—especially when you scale up.
Contact Us
Contact SNOWHITE CHEMICAL CO., LTD now to get COA, free samples and the latest quotation.
Email: shirley@snowhitechem.com
Phone: +86-25-56215758
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