What is 2-Chlorobenzyl chloride? (Synonyms: o-Chlorobenzyl chloride and alpha,2-Dichlorotoluene)
2-Chlorobenzyl chloride (CAS 611-19-8) is a clear liquid, colorless to pale yellow, with a pungent aromatic odor. You might also see it called o-Chlorobenzyl chloride or alpha,2-Dichlorotoluene. Its molecular formula is C₇H₆Cl₂, and EINECS number is 210-258-8.
We supply this compound as an intermediate for pharmaceutical, agrochemical, and dye synthesis. The chloromethyl group (-CH₂Cl) is highly reactive, which makes it useful in many organic synthesis routes.
Here are the key specifications for industrial use:
• Molecular weight: 161.03 g/mol
• Boiling point (atmospheric): 213–214℃
• Melting point: -13℃
• Density (25℃): 1.272–1.274 g/mL
• Refractive index (n20/D): 1.559
• Flash point (closed cup): 82℃
• Vapor density: 5.5 (vs air)
• Vapor pressure: 3 mmHg (84℃)
• Solubility: insoluble in water; soluble in ethanol, diethyl ether, benzene, chloroform, and similar organic solvents.
2-Chlorobenzyl chloride storage: How to keep it stable
Short-term storage (weeks) is fine in a closed, dry, dark container. But if you need to keep 2-Chlorobenzyl chloride for more than a couple of months, or you want to open the drum with purity still at its best, we recommend:
• Refrigeration at 0–10℃
• Nitrogen (or argon) blanketing inside the container
• Keeping it away from strong bases, oxidizers, and any heat source
We store everything this way in our warehouse, and customers consistently report that the material arrives in good condition.
Key applications of 2-Chlorobenzyl chloride (pharmaceutical and agrochemical uses)
Pharmaceuticals
It is a building block for ambenonium chloride (a reversible cholinesterase inhibitor) and various piperidine or benzothiazole derivatives.
Agrochemicals
This is a key raw material for the fungicide Prothioconazole and the herbicide Clomazone (also called dimethazone). Most of the inquiries we receive are from the pesticide sector.
Other industrial uses
You will also find it in azo dyes, acrylic dyes, pigments, plasticizers, rubber additives, coatings, and adhesives – essentially anywhere a reactive chloromethyl group is required.
2-Chlorobenzyl chloride safety – do not skip this part
2-Chlorobenzyl chloride is corrosive and hazardous. The GHS classification is as follows:
• Skin corrosion Category 1B – causes severe burns and eye damage
• Inhalation – may cause respiratory irritation, drowsiness or dizziness
• Aquatic toxicity Category 1 (H410) – very toxic to aquatic life with long-lasting effects
When handling this product, please:
• Wear chemical-resistant gloves, a face shield or goggles
• Work in a fume hood or a well-ventilated area
• Keep spill cleanup materials nearby
• Do not release it into drains or the environment
Ordering 2-Chlorobenzyl chloride from SNOWHITE CHEMICAL
Every batch we ship comes with a Certificate of Analysis (COA) and Safety Data Sheet (SDS). Purity meets industrial grade requirements. Packaging options are flexible: industrial drums or IBC totes are available. We use nitrogen blanketing and temperature control during shipping to maintain product stability.
We have stock available for immediate shipment. You may also reach out for a quote or to check inventory. Let us know your volume and packaging preference, and we will arrange delivery accordingly.
Frequently Asked Questions
What is the best long-term storage temperature for 2-Chlorobenzyl chloride?
0–10℃ refrigerated, under nitrogen.
Does 2-Chlorobenzyl chloride dissolve in water?
No. Use organic solvents such as ethanol, ether, benzene, or chloroform.
Where can I purchase stable, industrial-grade 2-Chlorobenzyl chloride?
SNOWHITE CHEMICAL CO., LTD. Every batch includes a COA.
What is the main agrochemical use of 2-Chlorobenzyl chloride?
It is used to produce Prothioconazole (fungicide) and Clomazone (herbicide).
What personal protective equipment is needed for handling 2-Chlorobenzyl chloride?
Chemical-resistant gloves, goggles or face shield, and a fume hood. Wash thoroughly after handling, and avoid release to the environment.
Contact Us
Contact SNOWHITE CHEMICAL CO., LTD now to get COA, free samples and the latest quotation.
Email: shirley@snowhitechem.com
Phone: +86-25-56215758
WhatsApp：+86-13776524331
