1. Overview of 2,6-Dichlorobenzaldehyde

2,6-Dichlorobenzaldehyde (CAS 83-38-5) is a halogenated aromatic aldehyde with high steric hindrance, widely used as a key regioselective building block in fine chemical synthesis.

SNOWHITE CHEMICAL CO.,LTD supplies bulk industrial grade and high-purity pharmaceutical grade products, with industry-leading isomer separation technology and strict genotoxic impurity control compliant with ICH standards.

Our products are widely used in large-scale API production, sulfonylurea herbicide manufacturing, high-performance liquid crystal materials and specialty chemicals worldwide.

Basic Chemical Information：

Chemical Name: 2,6-Dichlorobenzaldehyde

Molecular Formula: C₇H₄Cl₂O

Molecular Weight: 175.01 g/mol

CAS No.: 83-38-5

HS Code: 29130000

Appearance: White to off-white crystals or crystalline powder

UN NO: 3261

1.2 Functional Performance and Mechanism

The industrial application value of 2,6-Dichlorobenzaldehyde comes from the synergistic effect of aldehyde group and 2,6-dichloro substituents, which is the core difference from other isomers:

The aldehyde group has high cyclization reactivity, which can efficiently construct imidazole, thiazole and other heterocyclic structures required for pharmaceutical and agrochemical production, with high conversion rate and few by-products

The 2,6-ortho dichloro substituents have unique steric hindrance and electron-withdrawing effect, which can precisely regulate the regioselectivity of electrophilic substitution, and is the core structural guarantee for the biological activity of downstream drugs and agrochemicals

1.2.1 Practical Application Significance

The unique ortho-disubstituted structure of this product brings exclusive application advantages in industrial production:

• Pharmaceutical applications: The 2,6-dichlorophenyl pharmacophore is the key structure to enhance the binding affinity between drugs and targets, which is essential for the efficacy of antifungal, antibacterial and cardiovascular drugs
•  Agrochemical applications: The 2,6-disubstituted structure directly determines the selective herbicidal activity of sulfonylurea herbicides, ensuring crop safety and high production yield
• Industrial applications: It is the core aromatic unit for the synthesis of high-performance liquid crystals and optoelectronic materials, with stable structural performance

2.Pharmaceutical Grade 2,6-Dichlorobenzaldehyde

2.1 Product Overview

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2,6-Dichlorobenzaldehyde (≥99.0%) with strict isomer, residual solvent and genotoxic impurity control, compliant with ICH Q7 and pharmacopoeia standards, exclusively used as key intermediate for large-scale API synthesis. SNOWHITE CHEMICAL CO., LTD can provide customized quality standards and complete quality research documents according to your synthetic route.

2.2 Typical Applications

Mainly used in the synthesis of core intermediates for antifungal and cardiovascular drugs, directly participating in the construction of drug pharmacophores, with strict batch-to-batch consistency to ensure the safety and stability of final APIs.

3. Industrial Grade 2,6-Dichlorobenzaldehyde

3.1 Product Overview

used for large-scale synthesis of agrochemicals, dyes and specialty chemicals, focusing on production yield, cost control and stable bulk supply capacity.

3.2 Typical Applications

Widely used as core building block for the industrial production of sulfonylurea herbicides, ensuring high selective herbicidal activity and production yield; also used in the synthesis of high-performance azo dyes to enhance light and wash fastness, compatible with existing large-scale production lines.

4. Synthesis Processes

Industrial production of 2,6-Dichlorobenzaldehyde by SNOWHITE CHEMICAL CO.,LTD mainly adopts 2,6-dichlorotoluene selective oxidation process, with mature technology, stable isomer control, high conversion rate and batch consistency.

5. Quality

6. Packaging, Storage and Safety Information

6.1 Packaging

Standard: 1kg/5kg/25kg drums; customizable on request

6.2 Storage

Store in a cool, dry, well-ventilated, light-proof warehouse below 30°C，

Keep containers tightly sealed; store separately from incompatible materials

7. Supply and Technical Support by SNOWHITE CHEMICAL CO., LTD

SNOWHITE CHEMICAL CO., LTD provides stable and reliable global supply of 2,6-dichlorobenzaldehyde, with core competitive strengths:

ISO 9001 certified, strict batch-to-batch quality consistency control

Industry-leading isomer separation technology, customizable purity and impurity limits

Stable large-scale production capacity, fast delivery for standard bulk orders

Complete COA, SDS, TDS and full set of pharmaceutical registration documents available

Contact SNOWHITE CHEMICAL CO.,LTD now to get COA, free samples and the latest quotation.

Email: shirley@snowhitechem.com

Phone: +86-25-56215758.

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